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hi, you seem to have an exotic sound device there;

1. i can see you're using the jackdbus (D-Bus) interface; try not to at first: turn Setup/Misc/Other/Enable D-Bus interface off and try again.
2. you should try first setting Setup/Settings/Parameters/Interface = "hw:USB" and reset both Input/Output device to "(default)" or blank.
3. one recommendation for USB devices is also trying with Setup/Settings/Parameters/Sample Rate = 48000 and Periods/Buffer = 3.

hth.
cheers