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yes as long as the Alesis Trigger-iO USB interface is plugged in and up and running through ALSA snd-usb-audio/midi* kernel modules, it just becomes a matter to connect the right input MIDI port on drumkv1.

sure have to prepare setup a .drumkv1 preset file, along with all the sample files and upload it to the Rpi if not done in situ; probably you'll also want to run it as `drumkv1_jack --no-gui preset-file`.

check these out as well (thanks to Jeremy):
Raspberry Pi and realtime, low-latency audio
Using a Raspberry Pi as a drum machine: quick demo

hth.
cheers